{"id":1503,"date":"2021-10-05T09:18:00","date_gmt":"2021-10-05T13:18:00","guid":{"rendered":"https:\/\/www.therecoveryvillage.com\/?page_id=1503"},"modified":"2022-06-03T13:11:05","modified_gmt":"2022-06-03T17:11:05","slug":"buprenorphine","status":"publish","type":"page","link":"https:\/\/www.therecoveryvillage.com\/treatment-program\/addiction-medications\/buprenorphine\/","title":{"rendered":"Buprenorphine"},"content":{"rendered":"\n<h3>Buprenorphine is an opioid medication primarily used to treat addiction to other, more dangerous opioids. However, buprenorphine use can still carry some risks.<\/h3>\n\n\n\n<div class=\"is-layout-flow wp-block-group is-style-ataglance\"><div class=\"wp-block-group__inner-container\">\n<h3>Article at a Glance:<\/h3>\n\n\n\n<ul><li>Buprenorphine is one of two opioids approved for medication-assisted treatment (MAT) in the United States.<\/li><li>Buprenorphine is a partial opioid agonist; the effects are not as strong as other opioids, but it helps prevent opioid withdrawal.<\/li><li>Buprenorphine side effects are similar to those of other opioids, and the drug also has the potential for abuse and addiction.<\/li><\/ul>\n<\/div><\/div>\n\n\n\n<h2>What Is Buprenorphine?<\/h2>\n\n\n\n<p>Buprenorphine is a semi-synthetic opioid medication used for pain management as well as&nbsp;<a href=\"https:\/\/www.therecoveryvillage.com\/opiate-addiction\/\">opioid addiction<\/a>&nbsp;treatment. It was first developed in the&nbsp;<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK459126\/\" target=\"_blank\" rel=\"noreferrer noopener\">1960s<\/a>, and in 2002, it was&nbsp;<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2994593\/\" target=\"_blank\" rel=\"noreferrer noopener\">approved by the FDA<\/a>&nbsp;for use in opioid addiction treatment. In the past decade, it has gained increasing popularity as an alternative to&nbsp;<a href=\"https:\/\/www.therecoveryvillage.com\/methadone-addiction\/\">methadone<\/a>. Buprenorphine is available in different formulations under the brand names&nbsp;<a href=\"https:\/\/www.therecoveryvillage.com\/subutex-addiction\/\">Subutex<\/a>, Suboxone, Sublocade, Buprenex and Butrans.<\/p>\n\n\n\n<h2>How Buprenorphine Works<\/h2>\n\n\n\n<p><a href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2018\/020732s018lbl.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">Buprenorphine<\/a>&nbsp;is a partial agonist of mu opioid receptors, which are involved in processing pain signals in the body. Most prescription opioids are full agonists, meaning they attach much more tightly to opioid receptors. Because buprenorphine is a partial agonist, it has a weaker effect than opioids like oxycodone, fentanyl and heroin.<\/p>\n\n\n\n<p>When taken as prescribed, buprenorphine is a&nbsp;<a href=\"https:\/\/www.samhsa.gov\/medication-assisted-treatment\/medications-counseling-related-conditions\/buprenorphine\" target=\"_blank\" rel=\"noreferrer noopener\">safe and effective<\/a>&nbsp;medication for opioid use disorder. Buprenorphine has unique properties that reduce withdrawal symptoms and cravings, lower the potential for misuse and reduce overdose risks.<\/p>\n\n\n\n<h2>Using Buprenorphine for Opioid Addiction Treatment<\/h2>\n\n\n\n<p>Buprenorphine is primarily used to treat opioid use disorders. As a part of opioid replacement therapy, it can help patients manage cravings and withdrawal symptoms during&nbsp;<a href=\"https:\/\/www.therecoveryvillage.com\/treatment-program\/medical-detox\/\">drug detox<\/a>&nbsp;and ongoing treatment.<\/p>\n\n\n\n<h3>Opioid Replacement Therapy<\/h3>\n\n\n\n<p>Also called opioid maintenance therapy, medication-assisted treatment (<a href=\"https:\/\/www.drugabuse.gov\/publications\/research-reports\/medications-to-treat-opioid-addiction\/how-do-medications-to-treat-opioid-addiction-work\" target=\"_blank\" rel=\"noreferrer noopener\">MAT<\/a>) involves replacing more dangerous opioids like&nbsp;<a href=\"https:\/\/www.therecoveryvillage.com\/heroin-addiction\/\">heroin<\/a>&nbsp;or&nbsp;<a href=\"https:\/\/www.therecoveryvillage.com\/oxycodone-addiction\/\">oxycodone<\/a>&nbsp;with substitutes that last longer and produce less euphoric highs. Along with other forms of treatment, substitute opioids allow patients to manage cravings and withdrawal symptoms. Over time, patients are safely and gradually weaned off the opioid substitute.<\/p>\n\n\n\n<h2>Buprenorphine vs. Methadone<\/h2>\n\n\n\n<p>For many decades, the primary&nbsp;<a href=\"https:\/\/www.therecoveryvillage.com\/treatment-program\/addiction-medications\/\">opioid replacement drug<\/a>&nbsp;was methadone. However,&nbsp;<a href=\"https:\/\/www.drugabuse.gov\/publications\/research-reports\/medications-to-treat-opioid-addiction\/how-do-medications-to-treat-opioid-addiction-work\" target=\"_blank\" rel=\"noreferrer noopener\">studies suggest<\/a>&nbsp;that buprenorphine is similarly effective to methadone for opioid addiction treatment. Although buprenorphine interacts with some opioid receptors in the brain, it blocks others. This prevents other, more dangerous opioids from reacting with receptors if they\u2019re taken while buprenorphine is active.<\/p>\n\n\n\n<p>Unlike methadone, buprenorphine can be prescribed out of physician offices, making the medication more accessible. Because of its relative safety, buprenorphine has different prescription requirements than methadone. It also has a variety of formulations that methadone does not, including drug combinations like Suboxone (buprenorphine-naloxone) that reduce the risk of overdose.<\/p>\n\n\n\n<h2>Common Side Effects of Buprenorphine<\/h2>\n\n\n\n<p>Buprenorphine side effects are similar to those of other opioids. Commonly reported side effects&nbsp;<a href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2018\/020732s018lbl.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">include<\/a>:<\/p>\n\n\n\n<ul class=\"is-style-columns-3\"><li>Drowsiness or insomnia<\/li><li>Loss of coordination<\/li><li>Shallow breathing<\/li><li>Blurred vision<\/li><li>Constipation<\/li><li>Headache<\/li><li>Dizziness<\/li><li>Memory loss or difficulty concentrating<\/li><li>Dry mouth<\/li><li>Sexual dysfunction<\/li><\/ul>\n\n\n\n<h3>Withdrawal Syndrome<\/h3>\n\n\n\n<p>Buprenorphine is used to help mitigate withdrawal symptoms from other opioids. However, this medication can also create symptoms when someone stops taking it. Buprenorphine withdrawal symptoms may&nbsp;<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK526012\/\" target=\"_blank\" rel=\"noreferrer noopener\">include<\/a>:<\/p>\n\n\n\n<ul class=\"is-style-columns-3\"><li>Drug cravings<\/li><li>Nausea and vomiting<\/li><li>Headaches<\/li><li>Muscle aches<\/li><li>Insomnia<\/li><li>Lethargy<\/li><li>Digestive distress<\/li><li>Anxiety<\/li><li>Depression<\/li><li>Irritability<\/li><li>Fever or chills<\/li><li>Sweating<\/li><\/ul>\n\n\n\n<p>As with any drug treatment, it\u2019s important to follow the guidance of a doctor or clinic to manage symptoms and ensure safety.<\/p>\n\n\n\n<h2>Buprenorphine Misuse Potential<\/h2>\n\n\n\n<p>Despite being an effective drug for people recovering from opioid addiction, buprenorphine still has the potential for abuse and addiction. As an opioid, the drug causes the release of dopamine, a chemical involved in pleasure and addiction. For this reason, it is considered a&nbsp;<a href=\"https:\/\/www.deadiversion.usdoj.gov\/drug_chem_info\/buprenorphine.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">Schedule III<\/a>&nbsp;medication by the Drug Enforcement Agency (DEA).<\/p>\n\n\n\n<h2>Get More Information<\/h2>\n\n\n\n<p>If you are struggling with opioid addiction and considering treatment, The Recovery Village is here to help.&nbsp;<a href=\"https:\/\/www.therecoveryvillage.com\/contact\/\">Contact us<\/a>&nbsp;today to learn more about opioid addiction treatment programs that can help you get started on your recovery journey.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Buprenorphine is an opioid medication primarily used to treat addiction to other, more dangerous opioids. However, buprenorphine use can still carry some risks. Article at a Glance: Buprenorphine is one of two opioids approved for medication-assisted treatment (MAT) in the United States. Buprenorphine is a partial opioid agonist; the effects are not as strong as&#8230;<\/p>\n","protected":false},"author":8,"featured_media":0,"parent":1333,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"templates\/content-page-template.php","meta":{"_searchwp_excluded":"","_links_to":"","_links_to_target":""},"categories":[433],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v19.14 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Buprenorphine: What Is It, Uses for Opioid Addiction and More<\/title>\n<meta name=\"description\" content=\"Buprenorphine is often used to help treat opioid addiction. However, as an opioid itself, buprenorphine also carries the risk of abuse, dependence and addiction.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.therecoveryvillage.com\/treatment-program\/addiction-medications\/buprenorphine\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Buprenorphine: What Is It, Uses for Opioid Addiction and More\" \/>\n<meta property=\"og:description\" content=\"Buprenorphine is often used to help treat opioid addiction. 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